WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_TGGAAA_V$NFAT_Q4_01       ID:DB_ID:2437
C=1871; O=17; E=3.43; R=4.96; rawP=3.93e-08; adjP=7.70e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000080561 NA MID2 midline 2 11043 ENSG00000080561
2  ENSG00000166068 NA SPRED1 sprouty-related, EVH1 domain containing 1 161742 ENSG00000166068
3  ENSG00000147044 NA CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 8573 ENSG00000147044
4  ENSG00000145191 NA EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa 8893 ENSG00000145191
5  ENSG00000137770 NA CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 51496 ENSG00000137770
6  ENSG00000114573 NA ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 523 ENSG00000114573
7  ENSG00000064989 NA CALCRL calcitonin receptor-like 10203 ENSG00000064989
8  ENSG00000108854 NA SMURF2 SMAD specific E3 ubiquitin protein ligase 2 64750 ENSG00000108854
9  ENSG00000063854 NA HAGH hydroxyacylglutathione hydrolase 3029 ENSG00000063854
10  ENSG00000143924 NA EML4 echinoderm microtubule associated protein like 4 27436 ENSG00000143924
11  ENSG00000162695 NA SLC30A7 solute carrier family 30 (zinc transporter), member 7 148867 ENSG00000162695
12  ENSG00000117020 NA AKT3 v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) 10000 ENSG00000117020
13  ENSG00000118620 NA ZNF430 zinc finger protein 430 80264 ENSG00000118620
14  ENSG00000156052 NA GNAQ guanine nucleotide binding protein (G protein), q polypeptide 2776 ENSG00000156052
15  ENSG00000070961 NA ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 490 ENSG00000070961
16  ENSG00000214022 NA REPIN1 replication initiator 1 29803 ENSG00000214022
17  ENSG00000151576 NA QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 79691 ENSG00000151576


Database:Transcription Target       Name:hsa_V$HLF_01       ID:DB_ID:2030
C=253; O=7; E=0.46; R=15.10; rawP=4.45e-07; adjP=4.36e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000064989 NA CALCRL calcitonin receptor-like 10203 ENSG00000064989
2  ENSG00000166068 NA SPRED1 sprouty-related, EVH1 domain containing 1 161742 ENSG00000166068
3  ENSG00000147044 NA CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 8573 ENSG00000147044
4  ENSG00000155158 NA TTC39B tetratricopeptide repeat domain 39B 158219 ENSG00000155158
5  ENSG00000171365 NA CLCN5 chloride channel, voltage-sensitive 5 1184 ENSG00000171365
6  ENSG00000143924 NA EML4 echinoderm microtubule associated protein like 4 27436 ENSG00000143924
7  ENSG00000170604 NA IRF2BP1 interferon regulatory factor 2 binding protein 1 26145 ENSG00000170604


Database:Transcription Target       Name:hsa_CAGCTG_V$AP4_Q5       ID:DB_ID:2403
C=1502; O=13; E=2.75; R=4.72; rawP=3.28e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000080561 NA MID2 midline 2 11043 ENSG00000080561
2  ENSG00000138100 NA TRIM54 tripartite motif containing 54 57159 ENSG00000138100
3  ENSG00000166068 NA SPRED1 sprouty-related, EVH1 domain containing 1 161742 ENSG00000166068
4  ENSG00000147044 NA CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 8573 ENSG00000147044
5  ENSG00000138594 NA TMOD3 tropomodulin 3 (ubiquitous) 29766 ENSG00000138594
6  ENSG00000085449 NA WDFY1 WD repeat and FYVE domain containing 1 57590 ENSG00000085449
7  ENSG00000084764 NA MAPRE3 microtubule-associated protein, RP/EB family, member 3 22924 ENSG00000084764
8  ENSG00000114573 NA ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 523 ENSG00000114573
9  ENSG00000165617 NA DACT1 dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) 51339 ENSG00000165617
10  ENSG00000163517 NA HDAC11 histone deacetylase 11 79885 ENSG00000163517
11  ENSG00000170802 NA FOXN2 forkhead box N2 3344 ENSG00000170802
12  ENSG00000118194 NA TNNT2 troponin T type 2 (cardiac) 7139 ENSG00000118194
13  ENSG00000151576 NA QTRTD1 queuine tRNA-ribosyltransferase domain containing 1 79691 ENSG00000151576


Database:Transcription Target       Name:hsa_YTATTTTNR_V$MEF2_02       ID:DB_ID:2431
C=691; O=9; E=1.27; R=7.11; rawP=5.01e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000080561 NA MID2 midline 2 11043 ENSG00000080561
2  ENSG00000147044 NA CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 8573 ENSG00000147044
3  ENSG00000012983 NA MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 11183 ENSG00000012983
4  ENSG00000114573 NA ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 523 ENSG00000114573
5  ENSG00000165617 NA DACT1 dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) 51339 ENSG00000165617
6  ENSG00000101935 NA AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 9949 ENSG00000101935
7  ENSG00000118194 NA TNNT2 troponin T type 2 (cardiac) 7139 ENSG00000118194
8  ENSG00000143924 NA EML4 echinoderm microtubule associated protein like 4 27436 ENSG00000143924
9  ENSG00000108599 NA AKAP10 A kinase (PRKA) anchor protein 10 11216 ENSG00000108599


Database:Transcription Target       Name:hsa_WGGAATGY_V$TEF1_Q6       ID:DB_ID:2458
C=370; O=7; E=0.68; R=10.33; rawP=5.51e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118194 NA TNNT2 troponin T type 2 (cardiac) 7139 ENSG00000118194
2  ENSG00000138100 NA TRIM54 tripartite motif containing 54 57159 ENSG00000138100
3  ENSG00000166068 NA SPRED1 sprouty-related, EVH1 domain containing 1 161742 ENSG00000166068
4  ENSG00000138594 NA TMOD3 tropomodulin 3 (ubiquitous) 29766 ENSG00000138594
5  ENSG00000084764 NA MAPRE3 microtubule-associated protein, RP/EB family, member 3 22924 ENSG00000084764
6  ENSG00000137770 NA CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 51496 ENSG00000137770
7  ENSG00000165617 NA DACT1 dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) 51339 ENSG00000165617


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=14; E=4.49; R=3.12; rawP=0.0001; adjP=0.0020
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000104432 NA IL7 interleukin 7 3574 ENSG00000104432
2  ENSG00000136603 NA SKIL SKI-like oncogene 6498 ENSG00000136603
3  ENSG00000080561 NA MID2 midline 2 11043 ENSG00000080561
4  ENSG00000166068 NA SPRED1 sprouty-related, EVH1 domain containing 1 161742 ENSG00000166068
5  ENSG00000140575 NA IQGAP1 IQ motif containing GTPase activating protein 1 8826 ENSG00000140575
6  ENSG00000177666 NA PNPLA2 patatin-like phospholipase domain containing 2 57104 ENSG00000177666
7  ENSG00000101935 NA AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 9949 ENSG00000101935
8  ENSG00000103034 NA NDRG4 NDRG family member 4 65009 ENSG00000103034
9  ENSG00000164062 NA APEH N-acylaminoacyl-peptide hydrolase 327 ENSG00000164062
10  ENSG00000142661 NA MYOM3 myomesin family, member 3 127294 ENSG00000142661
11  ENSG00000108854 NA SMURF2 SMAD specific E3 ubiquitin protein ligase 2 64750 ENSG00000108854
12  ENSG00000185442 NA FAM174B family with sequence similarity 174, member B 400451 ENSG00000185442
13  ENSG00000143924 NA EML4 echinoderm microtubule associated protein like 4 27436 ENSG00000143924
14  ENSG00000214022 NA REPIN1 replication initiator 1 29803 ENSG00000214022


Database:Transcription Target       Name:hsa_V$PPAR_DR1_Q2       ID:DB_ID:2248
C=257; O=5; E=0.47; R=10.62; rawP=0.0001; adjP=0.0020
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005893 NA LAMP2 lysosomal-associated membrane protein 2 3920 ENSG00000005893
2  ENSG00000171365 NA CLCN5 chloride channel, voltage-sensitive 5 1184 ENSG00000171365
3  ENSG00000177666 NA PNPLA2 patatin-like phospholipase domain containing 2 57104 ENSG00000177666
4  ENSG00000070961 NA ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 490 ENSG00000070961
5  ENSG00000101473 NA ACOT8 acyl-CoA thioesterase 8 10005 ENSG00000101473


Database:Transcription Target       Name:hsa_V$CEBPB_02       ID:DB_ID:1922
C=252; O=5; E=0.46; R=10.83; rawP=0.0001; adjP=0.0020
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000166068 NA SPRED1 sprouty-related, EVH1 domain containing 1 161742 ENSG00000166068
2  ENSG00000147044 NA CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 8573 ENSG00000147044
3  ENSG00000171940 NA ZNF217 zinc finger protein 217 7764 ENSG00000171940
4  ENSG00000155158 NA TTC39B tetratricopeptide repeat domain 39B 158219 ENSG00000155158
5  ENSG00000137770 NA CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 51496 ENSG00000137770


Database:Transcription Target       Name:hsa_V$MAF_Q6       ID:DB_ID:2188
C=256; O=5; E=0.47; R=10.66; rawP=0.0001; adjP=0.0020
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005893 NA LAMP2 lysosomal-associated membrane protein 2 3920 ENSG00000005893
2  ENSG00000106799 NA TGFBR1 transforming growth factor, beta receptor 1 7046 ENSG00000106799
3  ENSG00000012983 NA MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 11183 ENSG00000012983
4  ENSG00000137770 NA CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 51496 ENSG00000137770
5  ENSG00000117020 NA AKT3 v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma) 10000 ENSG00000117020


Database:Transcription Target       Name:hsa_V$COUP_DR1_Q6       ID:DB_ID:2250
C=246; O=5; E=0.45; R=11.10; rawP=9.26e-05; adjP=0.0020
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005893 NA LAMP2 lysosomal-associated membrane protein 2 3920 ENSG00000005893
2  ENSG00000177666 NA PNPLA2 patatin-like phospholipase domain containing 2 57104 ENSG00000177666
3  ENSG00000070961 NA ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 490 ENSG00000070961
4  ENSG00000163517 NA HDAC11 histone deacetylase 11 79885 ENSG00000163517
5  ENSG00000101473 NA ACOT8 acyl-CoA thioesterase 8 10005 ENSG00000101473




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).